What is Systems Biology ?

Nowadays, the major hurdles to obtain bulk genomic information have been overcome and high-throughput methods for measuring global expression of RNA, proteins and metabolites (genomics, proteomics and metabolomics) have been developed. To gain an understanding of biology at a higher level, with its complex collection of networks and pathways, the ~omics have to been pulled together in an approach called systems biology. However, the term systems biology can be understood in different ways....

A new approach to decoding life: systems biology. Institute for Systems Biology, Seattle

The map of the genome is just the rule book; "systems biology" is the ball game. Stikeman, Upstream 2002

Systems biology simultaneously studies the complex interaction of many levels of biological information to understand how they work together. http://www.systemsbiology.org/

"The computer simulation of life." Kitano, Nature 2003

Systems biology looks at how the components work together as a system. Biomolecular Systems

The Systems Biology Center aims at the discovery of useful functionalities buried in the "Book of Life". http://www-ict.its.tudelft.nl/~imds/

Systems biology is high-throughput reductionism. Katagiri, Plant Physiology 2003

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Wageningen UniversityBiowise

For further information or ideas please contact Dr. I. Rienties or Dr. P. Schaap